Cargando…

Role of the metastasis-promoting protein osteopontin in the tumour microenvironment

Osteopontin (OPN) is a secreted protein present in bodily fluids and tissues. It is subject to multiple post-translational modifications, including phosphorylation, glycosylation, proteolytic cleavage and crosslinking by transglutamination. Binding of OPN to integrin and CD44 receptors regulates sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anborgh, Pieter H, Mutrie, Jennifer C, Tuck, Alan B, Chambers, Ann F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2010
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822994/ https://www.ncbi.nlm.nih.gov/pubmed/20597997 http://dx.doi.org/10.1111/j.1582-4934.2010.01115.x

Ejemplares similares

Role of osteopontin in tumour progression
por: Rittling, S R, et al.
Publicado: (2004)

Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial
por: Bramwell, Vivien HC, et al.
Publicado: (2014)

Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis
por: Krstic, Milica, et al.
Publicado: (2019)

Increased Circulating Osteopontin Levels Promote Primary Tumour Growth, but Do Not Induce Metastasis in Melanoma
por: Saup, Rafael, et al.
Publicado: (2023)

The role of osteopontin in the progression of solid organ tumour
por: Zhao, Hailin, et al.
Publicado: (2018)

Osteopontin binds ICOSL promoting tumor metastasis
por: Raineri, Davide, et al.
Publicado: (2020)

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response
por: Thoms, J W, et al.
Publicado: (2012)

Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis
por: Wong, G S, et al.
Publicado: (2013)

Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays
por: Rodenhiser, David I, et al.
Publicado: (2008)

MicroRNAs in Metastasis and the Tumour Microenvironment
por: Solé, Carla, et al.
Publicado: (2021)

Molecular biology of breast cancer metastasis: Clinical implications of experimental studies on metastatic inefficiency
por: Chambers, Ann F, et al.
Publicado: (2000)

Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis
por: Höppener, Diederik J., et al.
Publicado: (2020)

The role of the tumour microenvironment in the angiogenesis of pituitary tumours
por: Marques, Pedro, et al.
Publicado: (2020)

Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin
por: Jessen, Katayoun Alavi, et al.
Publicado: (2004)

Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation
por: Samant, Rajeev S, et al.
Publicado: (2007)

Functional Characterization of Stromal Osteopontin in Melanoma Progression and Metastasis
por: Kumar, Santosh, et al.
Publicado: (2013)

Osteopontin-Enhanced Hepatic Metastasis of Colorectal Cancer Cells
por: Huang, Jianjin, et al.
Publicado: (2012)

Down-regulation of osteopontin attenuates breast tumour progression in vivo
por: Chakraborty, Goutam, et al.
Publicado: (2008)

The Role of CDK5 in Tumours and Tumour Microenvironments
por: Do, Phuong Anh, et al.
Publicado: (2020)

The Phylogeny of Osteopontin—Analysis of the Protein Sequence
por: Weber, Georg F.
Publicado: (2018)

Suppression of tumour growth by orally administered osteopontin is accompanied by alterations in tumour blood vessels
por: Rittling, S R, et al.
Publicado: (2014)

The role of osteopontin in inflammatory processes
por: Lund, Susan Amanda, et al.
Publicado: (2009)

Role of Osteopontin in Liver Diseases
por: Wen, Yankai, et al.
Publicado: (2016)

The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways
por: Courter, Donald, et al.
Publicado: (2010)

C‐C chemokine receptor type 1 mediates osteopontin‐promoted metastasis in hepatocellular carcinoma
por: Zhu, Ying, et al.
Publicado: (2018)

Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
por: Jia, Rongjie, et al.
Publicado: (2016)

Conditional Knockdown of Osteopontin Inhibits Breast Cancer Skeletal Metastasis
por: Kovacheva, Marineta, et al.
Publicado: (2019)

Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number
por: Andrews, Joseph, et al.
Publicado: (2010)

Quantitative Analysis of Protein Evolution: The Phylogeny of Osteopontin
por: Wang, Xia, et al.
Publicado: (2021)

Genetic polymorphisms in the osteopontin promoter increases the risk of distance metastasis and death in Chinese patients with gastric cancer
por: Zhao, Fujun, et al.
Publicado: (2012)

Role of Osteopontin in Idiopathic Pulmonary Fibrosis
Publicado: (2005)

Role of Osteopontin in Psoriasis: An Immunohistochemical Study
por: Abdel-Mawla, M Yousry, et al.
Publicado: (2016)

Role of Osteopontin in Systemic Lupus Erythematosus
por: Kaleta, Beata
Publicado: (2014)

The Role of Osteopontin in Respiratory Health and Disease
por: Barkas, Georgios I., et al.
Publicado: (2023)

Role of osteopontin in cancer development and treatment
por: Yan, Zhihua, et al.
Publicado: (2023)

The Multifaceted Role of Osteopontin in Prostate Pathologies
por: Silver, Samara V., et al.
Publicado: (2023)

Role for extracellular vesicles in the tumour microenvironment
por: O'Loghlen, Ana
Publicado: (2018)

Role of extracellular vesicles in tumour microenvironment
por: Tao, Shi-Cong, et al.
Publicado: (2020)

Roles of circRNAs in the tumour microenvironment
por: Zhang, Qiuge, et al.
Publicado: (2020)

Important functional role of the protein osteopontin in the progression of malignant pleural mesothelioma
por: Digifico, Elisabeth, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tkld39s05pvci5225vdfi033m4