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Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo

Oncostatin M (OSM) is a pleiotropic cytokine of the IL-6 family and displays both pro-inflammatory and anti-inflammatory activities. We studied the impact of OSM on the gene activation profile of human synovial cells, which play a central role in the progression of inflammatory responses in joints....

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Detalles Bibliográficos
Autores principales: Dumas, Aline, Lagarde, Stéphanie, Laflamme, Cynthia, Pouliot, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823080/
https://www.ncbi.nlm.nih.gov/pubmed/21854541
http://dx.doi.org/10.1111/j.1582-4934.2011.01412.x

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