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Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo
Oncostatin M (OSM) is a pleiotropic cytokine of the IL-6 family and displays both pro-inflammatory and anti-inflammatory activities. We studied the impact of OSM on the gene activation profile of human synovial cells, which play a central role in the progression of inflammatory responses in joints....
Autores principales: | Dumas, Aline, Lagarde, Stéphanie, Laflamme, Cynthia, Pouliot, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823080/ https://www.ncbi.nlm.nih.gov/pubmed/21854541 http://dx.doi.org/10.1111/j.1582-4934.2011.01412.x |
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