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Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway

Compound K (20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, CK), an intestinal bacterial metabolite of panaxoside, has been shown to inhibit tumour growth in a variety of tumours. However, the mechanisms involved are largely unknown. We use human gastric carcinoma cell lines BGC823, SGC7901 and human...

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Detalles Bibliográficos
Autores principales: Hu, Chun, Song, Gang, Zhang, Bing, Liu, Zhongchen, Chen, Rong, Zhang, Hong, Hu, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823096/
https://www.ncbi.nlm.nih.gov/pubmed/21323864
http://dx.doi.org/10.1111/j.1582-4934.2011.01278.x