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A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling

Platinum anticancer drugs have been used for three decades despite their serious side effects and the emerging of resistance phenomena. Recently, a phosphine copper(I) complex, [Cu(thp)(4)][PF(6)] (CP), gained special attention because of its strong antiproliferative effects. CP killed human colon c...

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Detalles Bibliográficos
Autores principales: Gandin, Valentina, Pellei, Maura, Tisato, Francesco, Porchia, Marina, Santini, Carlo, Marzano, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823100/
https://www.ncbi.nlm.nih.gov/pubmed/21388518
http://dx.doi.org/10.1111/j.1582-4934.2011.01292.x