Targeting and retention of HPV16 E7 to the endoplasmic reticulum enhances immune tumour protection

The endoplasmic reticulum (ER) is where the major histocompatibility complex (MHC) class I molecules are loaded with epitopes to cause an immune cellular response. Most of the protein antigens are degraded in the cytoplasm to amino acids and few epitopes reach the ER. Antigen targeting of this organ...

Descripción completa

Detalles Bibliográficos
Autores principales: Loera-Arias, MJ, Martínez-Pérez, AG, Barrera-Hernández, A, Ibarra-Obregón, ER, González-Saldívar, G, Martínez-Ortega, JI, Rosas-Taraco, A, Villanueva-Olivo, A, Esparza-González, SC, Villatoro-Hernandez, J, Saucedo-Cárdenas, O, Montes-de-Oca-Luna, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823120/
https://www.ncbi.nlm.nih.gov/pubmed/19818090
http://dx.doi.org/10.1111/j.1582-4934.2009.00934.x

Ejemplares similares

Ejemplares similares