Cargando…

Akt-mediated anti-apoptotic effects of substance P in Anti-Fas-induced apoptosis of human tenocytes

Substance P (SP) and its receptor, the neurokinin-1 receptor (NK-1 R), are expressed by human tenocytes, and they are both up-regulated in cases of tendinosis, a condition associated with excessive apoptosis. It is known that SP can phosphorylate/activate the protein kinase Akt, which has anti-apopt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Backman, Ludvig J, Danielson, Patrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823176/ https://www.ncbi.nlm.nih.gov/pubmed/23577779 http://dx.doi.org/10.1111/jcmm.12059

Ejemplares similares

Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation
por: Backman, Ludvig J, et al.
Publicado: (2014)

Substance P Is a Mechanoresponsive, Autocrine Regulator of Human Tenocyte Proliferation
por: Backman, Ludvig J., et al.
Publicado: (2011)

The effects of substance P and acetylcholine on human tenocyte proliferation converge mechanistically via TGF-β1
por: Fong, Gloria, et al.
Publicado: (2017)

Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway
por: Fong, Gloria, et al.
Publicado: (2012)

The tenocyte phenotype of human primary tendon cells in vitro is reduced by glucocorticoids
por: Spang, Christoph, et al.
Publicado: (2016)

Substance P and patterned silk biomaterial stimulate periodontal ligament stem cells to form corneal stroma in a bioengineered three-dimensional model
por: Chen, Jialin, et al.
Publicado: (2017)

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway
por: Yuan, Yan, et al.
Publicado: (2018)

Increased susceptibility of osteoarthritis tenocytes to FasL-induced apoptosis is associated with elevated expression of Fas receptor but no alterations in the expression of Sentrin-1/SUMO-1
por: Machner, A, et al.
Publicado: (2003)

Ciliary Neurotrophic Factor Promotes the Migration of Corneal Epithelial Stem/progenitor Cells by Up-regulation of MMPs through the Phosphorylation of Akt
por: Chen, Jialin, et al.
Publicado: (2016)

FLASH Knockdown Sensitizes Cells To Fas-Mediated Apoptosis via Down-Regulation of the Anti-Apoptotic Proteins, MCL-1 and Cflip Short
por: Chen, Song, et al.
Publicado: (2012)

Apoptotic Body-Rich Media from Tenocytes Enhance Proliferation and Migration of Tenocytes and Bone Marrow Stromal Cells
por: Dong, Chenhui, et al.
Publicado: (2022)

Secretome from In Vitro Mechanically Loaded Myoblasts Induces Tenocyte Migration, Transition to a Fibroblastic Phenotype and Suppression of Collagen Production
por: Zhou, Xin, et al.
Publicado: (2021)

Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: Comparison between two model systems
por: Backman, L J, et al.
Publicado: (2013)

Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
por: Zhou, Xin, et al.
Publicado: (2021)

Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis
por: Gajate, Consuelo, et al.
Publicado: (2004)

Tumor Necrosis Factor‐α Gene Transfer Augments Anti‐Fas Antibody‐mediated Apoptosis in Human Glioma Cells
por: Mizuno, Masaaki, et al.
Publicado: (1996)

Transforming Growth Factor Beta 1 Modulates the Functional Expression of the Neurokinin-1 Receptor in Human Keratocytes
por: Roux, Sandrine Le, et al.
Publicado: (2016)

Keratocyte Differentiation Is Regulated by NF-κB and TGFβ Signaling Crosstalk
por: Zhou, Xin, et al.
Publicado: (2022)

Camptothecin sensitizes androgen-independent prostate cancer cells to anti-Fas-induced apoptosis
por: Costa-Pereira, A P, et al.
Publicado: (1999)

The effect of cyclophosphamide on Fas-mediated apoptosis.
por: Lee, J. H., et al.
Publicado: (1997)

Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor-α in periarticular tenocytes from patients with knee joint osteoarthritis
por: Machner, Andreas, et al.
Publicado: (2003)

Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/Fas L-Mediated Apoptotic Signaling
por: Kim, Mi Hye, et al.
Publicado: (2014)

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody
Publicado: (1995)

Substance P induces fibrotic changes through activation of the RhoA/ROCK pathway in an in vitro human corneal fibrosis model
por: Słoniecka, Marta, et al.
Publicado: (2019)

Crosstalk Influence between P38MAPK and Autophagy on Mitochondria-Mediated Apoptosis Induced by Anti-Fas Antibody/Actinomycin D in Human Hepatoma Bel-7402 Cells
por: Wang, Yu, et al.
Publicado: (2017)

Akt-Fas to Quell Aberrant T Cell Differentiation and Apoptosis in Covid-19
por: Leonardi, Anthony J., et al.
Publicado: (2020)

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids
Publicado: (1995)

In Vitro Study of the Anti-inflammatory and Antifibrotic Activity of Tannic Acid-Coated Curcumin-Loaded Nanoparticles in Human Tenocytes
por: Molinaro, Giuseppina, et al.
Publicado: (2023)

Low‐dose radiation prevents type 1 diabetes‐induced cardiomyopathy via activation of AKT mediated anti‐apoptotic and anti‐oxidant effects
por: Zhang, Fangfang, et al.
Publicado: (2016)

Mechanical stress potentiates the differentiation of periodontal ligament stem cells into keratocytes
por: Chen, Jialin, et al.
Publicado: (2018)

Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2015)

Anti-Fas IgM monoclonal antibody (anti-Fas mAb) effect on haemophilic arthropathy (HA) synoviocytes
por: Guiducci, Serena, et al.
Publicado: (2012)

Regulation of Hypoxia-Induced Cell Death in Human Tenocytes
por: Liang, Min, et al.
Publicado: (2012)

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages
por: Kiener, Peter A., et al.
Publicado: (1997)

AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1
por: Ishigaki, Shinsuke, et al.
Publicado: (2009)

Opium induces apoptosis in Jurkat cells via promotion of pro-apoptotic and inhibition of anti-apoptotic molecules
por: Arababadi, Mohammad Kazemi, et al.
Publicado: (2016)

The Fas/FasL System in Reproduction: Survival and Apoptosis
por: Mor, Gil, et al.
Publicado: (2002)

Phyllanthus urinaria Induces Apoptosis in Human Osteosarcoma 143B Cells via Activation of Fas/FasL- and Mitochondria-Mediated Pathways
por: Wu, Hsin-Yi, et al.
Publicado: (2012)

Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia
por: Ullah, Irfan, et al.
Publicado: (2018)

Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells
por: Spang, Christoph, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ao47n6t81dqfc8k5h81li8o4rc