Cargando…

Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway

Clinical trials have shown that angiotensin II receptor blockers reduce the new onset of diabetes in hypertensives; however, the underlying mechanisms remain unknown. We investigated the effects of telmisartan on peroxisome proliferator activated receptor γ (PPAR-δ) and the adenosine monophosphate (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Xiaoli, Luo, Zhidan, Ma, Liqun, Ma, Shuangtao, Yang, Dachun, Zhao, Zhigang, Yan, Zhencheng, He, Hongbo, Cao, Tingbing, Liu, Daoyan, Zhu, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823201/ https://www.ncbi.nlm.nih.gov/pubmed/20477906 http://dx.doi.org/10.1111/j.1582-4934.2010.01085.x

Ejemplares similares

Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels
por: Chen, Xiaoping, et al.
Publicado: (2010)

Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS
por: Zhao, Zhigang, et al.
Publicado: (2011)

Telmisartan Improves Insulin Resistance of Skeletal Muscle Through Peroxisome Proliferator–Activated Receptor-δ Activation
por: Li, Li, et al.
Publicado: (2013)

Attenuation of Immune-Mediated Renal Injury by Telmisartan, an Angiotensin Receptor Blocker and a Selective PPAR-γ Activator
por: Hamano, Yuki, et al.
Publicado: (2011)

Angiotensin receptor blocker telmisartan suppresses renal gluconeogenesis during starvation
por: Tojo, Akihiro, et al.
Publicado: (2015)

TRPV1 Activation Attenuates High-Salt Diet-Induced Cardiac Hypertrophy and Fibrosis through PPAR-δ Upregulation
por: Gao, Feng, et al.
Publicado: (2014)

Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan
por: Park, Jung Gyu, et al.
Publicado: (2019)

Angiotensin II receptor blocker telmisartan attenuates aortic stiffening and remodelling in STZ-diabetic rats
por: Salum, Erik, et al.
Publicado: (2014)

Telmisartan improves cardiac fibrosis in diabetes through peroxisome proliferator activated receptor δ (PPARδ): from bedside to bench
por: Chang, Wei-Ting, et al.
Publicado: (2016)

Regulation of Muscle Fiber Type and Running Endurance by PPARδ
por: Wang, Yong-Xu, et al.
Publicado: (2004)

Telmisartan Activates PPARδ to Improve Symptoms of Unpredictable Chronic Mild Stress-Induced Depression in Mice
por: Li, Yingxiao, et al.
Publicado: (2017)

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance
por: Aguilar-Recarte, David, et al.
Publicado: (2021)

Correction: Regulation of Muscle Fiber Type and Running Endurance by PPARδ
Publicado: (2005)

Angiotensin II type 1 receptor blocker telmisartan induces apoptosis and autophagy in adult T‐cell leukemia cells
por: Kozako, Tomohiro, et al.
Publicado: (2016)

Angiotensin receptor blocker telmisartan inhibits cell proliferation and tumor growth of cholangiocarcinoma through cell cycle arrest
por: Samukawa, Eri, et al.
Publicado: (2017)

Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection
por: Attia, Yasmeen M, et al.
Publicado: (2013)

Transient Receptor Potential Vanilloid 1 Activation Enhances Gut Glucagon-Like Peptide-1 Secretion and Improves Glucose Homeostasis
por: Wang, Peijian, et al.
Publicado: (2012)

PPARδ: A Potential Therapeutic Target for the Treatment of Metabolic Hypertension
por: Jiang, Yanli, et al.
Publicado: (2019)

Potential of angiotensin II receptor blocker telmisartan in reducing mortality among hospitalized patients with COVID-19 compared with recommended drugs
por: Liu, Dengyuan, et al.
Publicado: (2022)

Sodium‐Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt‐Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling
por: Zhao, Yu, et al.
Publicado: (2022)

The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor
por: Liu, Yi, et al.
Publicado: (2018)

Combined pharmacological activation of AMPK and PPAR δ potentiates the effects of exercise in trained mice
por: Manio, Mark Christian C., et al.
Publicado: (2016)

An Angiotensin II (Ang II) Type 1 Receptor Blocker, Telmisartan, Improves Insulin Resistance in KK-A(y) Diabetic Mice
por: Takasu, Toshiyuki, et al.
Publicado: (2006)

Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke
por: Kikuchi, Kiyoshi, et al.
Publicado: (2013)

Telmisartan-induced sprue-like enteropathy: a case report and a review of patients using non-olmesartan angiotensin receptor blockers
por: Mandavdhare, Harshal Surendra, et al.
Publicado: (2017)

The role of the angiotensin II type I receptor blocker telmisartan in the treatment of non-alcoholic fatty liver disease: a brief review
por: Borém, Luciana M. A., et al.
Publicado: (2018)

The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice
por: Nickel, Laura, et al.
Publicado: (2022)

A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice
por: Chen, Wei, et al.
Publicado: (2015)

Increase in muscle endurance in mice by dietary Yamabushitake mushroom (Hericium erinaceus) possibly via activation of PPARδ
por: Komiya, Yusuke, et al.
Publicado: (2019)

NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
por: Mackenzie, Gerardo G., et al.
Publicado: (2008)

Anti-Diabetic Effect of Telmisartan Through its Partial PPARγ-Agonistic Activity
por: Ayza, Muluken Altaye, et al.
Publicado: (2020)

AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth
por: Ding, Jiajun, et al.
Publicado: (2021)

PPAR-δ in Vascular Pathophysiology
por: Wang, Nanping
Publicado: (2008)

Long-term, up to 18 months, protective effects of the angiotensin II receptor blocker telmisartan on Epirubin-induced inflammation and oxidative stress assessed by serial strain rate
por: Dessì, Mariele, et al.
Publicado: (2013)

Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease
por: You, Mei, et al.
Publicado: (2022)

Telmisartan Potentiates Insulin Secretion via Ion Channels, Independent of the AT1 Receptor and PPARγ
por: Liu, Tao, et al.
Publicado: (2021)

Association of angiotensin-converting enzyme 2 gene A/G polymorphism and elevated blood pressure in Chinese patients with metabolic syndrome
por: Zhong, Jian, et al.
Publicado: (2006)

PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy
por: Chen, Miao, et al.
Publicado: (2021)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
por: Glazer, Robert I., et al.
Publicado: (2008)

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo
por: Higgins, Larry G., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7qm2r3dckik6q9lubc5pj5h637