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Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression

The thioredoxin system is a promising target when aiming to overcome the problem of clinical radiation resistance. Altered cellular redox status and redox sensitive thiols contributing to induction of resistance strongly connect the ubiquitous redox enzyme thioredoxin reductase (TrxR) to the cellula...

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Detalles Bibliográficos
Autores principales:	Selenius, Markus, Hedman, Mattias, Brodin, David, Gandin, Valentina, Rigobello, Maria Pia, Flygare, Jenny, Marzano, Christine, Bindoli, Alberto, Brodin, Ola, Björnstedt, Mikael, Fernandes, Aristi P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823227/ https://www.ncbi.nlm.nih.gov/pubmed/22003958 http://dx.doi.org/10.1111/j.1582-4934.2011.01469.x

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