Cell cloning-based transcriptome analysis in Rett patients: relevance to the pathogenesis of Rett syndrome of new human MeCP2 target genes

More than 90% of Rett syndrome (RTT) patients have heterozygous mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene that encodes the methyl-CpG-binding protein 2, a transcriptional modulator. Because MECP2 is subjected to X chromosome inactivation (XCI), girls with RTT either express...

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Detalles Bibliográficos
Autores principales: Nectoux, J, Fichou, Y, Rosas-Vargas, H, Cagnard, N, Bahi-Buisson, N, Nusbaum, P, Letourneur, F, Chelly, J, Bienvenu, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823278/
https://www.ncbi.nlm.nih.gov/pubmed/20569274
http://dx.doi.org/10.1111/j.1582-4934.2010.01107.x

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