Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies

Tyrosine kinase fusion genes represent an important class of oncogenes associated with leukaemia and solid tumours. They are produced by translocations and other chromosomal rearrangements of a subset of tyrosine kinase genes, including ABL, PDGFRA, PDGFRB, FGFR1, SYK, RET, JAK2 and ALK. Based on re...

Descripción completa

Detalles Bibliográficos
Autores principales: Medves, Sandrine, Demoulin, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823288/
https://www.ncbi.nlm.nih.gov/pubmed/21854543
http://dx.doi.org/10.1111/j.1582-4934.2011.01415.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823288/
https://www.ncbi.nlm.nih.gov/pubmed/21854543
http://dx.doi.org/10.1111/j.1582-4934.2011.01415.x

Ejemplares similares