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Membrane-targeted strategies for modulating APP and Aβ-mediated toxicity

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by numerous pathological features including the accumulation of neurotoxic amyloid-β (Aβ) peptide. There is currently no effective therapy for AD, but the development of therapeutic strategies that target the cell...

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Detalles Bibliográficos
Autores principales: Price, Katherine A, Crouch, Peter J, Donnelly, Paul S, Masters, Colin L, White, Anthony R, Curtain, Cyril C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823352/
https://www.ncbi.nlm.nih.gov/pubmed/19278455
http://dx.doi.org/10.1111/j.1582-4934.2008.00642.x