Cargando…

Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model

Casein kinase II (CK2) inhibitors suppress cancer cell growth. In this study, we examined the inhibitory effects of a novel CK2 inhibitor, hematein, on tumor growth in a murine xenograft model. We found that in lung cancer cells, hematein inhibited cancer cell growth, Akt/PKB Ser129 phosphorylation,...

Descripción completa

Detalles Bibliográficos
Autores principales:	HUNG, MING-SZU, XU, ZHIDONG, CHEN, YU, SMITH, EMMANUEL, MAO, JIAN-HUA, HSIEH, DAVID, LIN, YU-CHING, YANG, CHENG-TA, JABLONS, DAVID M., YOU, LIANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823374/ https://www.ncbi.nlm.nih.gov/pubmed/24008396 http://dx.doi.org/10.3892/ijo.2013.2087

Ejemplares similares

Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
por: Hung, Ming-Szu, et al.
Publicado: (2009)

Functional Polymorphism of the CK2α Intronless Gene Plays Oncogenic Roles in Lung Cancer
por: Hung, Ming-Szu, et al.
Publicado: (2010)

Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene
por: Wang, Yang, et al.
Publicado: (2015)

Coumestrol from the national cancer Institute’s natural product library is a novel inhibitor of protein kinase CK2
por: Liu, Shu, et al.
Publicado: (2013)

Cul4A is an oncogene in malignant pleural mesothelioma
por: Hung, Ming-Szu, et al.
Publicado: (2011)

Effects of okadaic acid and hematein on human lung adenocarcinoma A549 cells and responses of mitochondria and endoplasmic reticulum apoptosis pathways
por: Wang, Renjun, et al.
Publicado: (2019)

Casein kinase II is a predominantly nuclear enzyme
Publicado: (1992)

Immunocytochemical localization of casein kinase II during interphase and mitosis
Publicado: (1991)

Tubulin phosphorylation by casein kinase II is similar to that found in vivo
Publicado: (1987)

Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer
por: Bravo, Dawn T, et al.
Publicado: (2013)

Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression
por: Lu, Chenyang, et al.
Publicado: (2023)

The Drosophila Splicing Factor PSI Is Phosphorylated by Casein Kinase II and Tousled-Like Kinase
por: Taliaferro, J. Matthew, et al.
Publicado: (2013)

Crosstalk between casein kinase II and Ste20-related kinase Nak1
por: Cipak, Lubos, et al.
Publicado: (2013)

Cucurbitacin E inhibits the Yes-associated protein signaling pathway and suppresses brain metastasis of human non-small cell lung cancer in a murine model
por: Hsu, Ping-Chih, et al.
Publicado: (2019)

Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells
por: Hung, Ming‐Szu, et al.
Publicado: (2016)

Casein Kinase 2 Signaling in White Matter Stroke
por: Nguyen, Hung, et al.
Publicado: (2022)

Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma()()()
por: Zakharia, Kais, et al.
Publicado: (2018)

STUDIES ON THE FORMATION AND IONIZATION OF THE COMPOUNDS OF CASEIN WITH ALKALI : II. THE CONDUCTIVITIES OF ALKALI CASEINATE SOLUTIONS.
por: Greenberg, David M., et al.
Publicado: (1924)

PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer
por: WANG, Yang, et al.
Publicado: (2015)

The C. elegans Casein Kinase II is associated with meiotic DNA in fertilized oocytes
por: Yim, Nahyun, et al.
Publicado: (2022)

Targeting Casein Kinase 1 (CK1) in Hematological Cancers
por: Janovská, Pavlína, et al.
Publicado: (2020)

Casein kinase signaling in axon regeneration
por: Ayad, Nagi G., et al.
Publicado: (2016)

Editorial: Casein kinases in human diseases
por: Venerando, Andrea, et al.
Publicado: (2022)

Cul4A Modulates Invasion and Metastasis of Lung Cancer through Regulation of ANXA10
por: Hung, Ming-Szu, et al.
Publicado: (2019)

Influence of Chymosin on Physicochemical and Hydrolysis Characteristics of Casein Micelles and Individual Caseins
por: Chen, Chun-Chi, et al.
Publicado: (2021)

Casein Kinase 2 inhibition sensitizes medulloblastoma to temozolomide
por: Nitta, Ryan T., et al.
Publicado: (2019)

Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia
por: Richter, Anna, et al.
Publicado: (2019)

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia
por: Song, C, et al.
Publicado: (2016)

Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na(+) channel
por: Abd El-Aziz, Tarek Mohamed, et al.
Publicado: (2021)

Inhibition of yes‐associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model
por: Hsu, Ping‐Chih, et al.
Publicado: (2018)

Survival-associated factors of first-line EGFR-tyrosine kinase inhibitor responders and non-responders in lung adenocarcinoma patients with common EGFR mutations
por: Hung, Ming-Szu, et al.
Publicado: (2018)

Casein kinase II–dependent phosphorylation of DNA topoisomerase II suppresses the effect of a catalytic topo II inhibitor, ICRF-193, in fission yeast
por: Nakazawa, Norihiko, et al.
Publicado: (2019)

Casein Kinase 1 and Human Disease: Insights From the Circadian Phosphoswitch
por: Francisco, Joel C., et al.
Publicado: (2022)

Correction: Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide
por: Nitta, Ryan T., et al.
Publicado: (2019)

Casein kinase1α activators, a precision weapon for CRC
por: Li, Bin, et al.
Publicado: (2017)

Casein Kinase II Inhibitor Enhances Production of Infectious Genotype 1a Hepatitis C Virus (H77S)
por: Kim, Seungtaek, et al.
Publicado: (2014)

Erythrocytic Casein Kinase II Regulates Cytoadherence of Plasmodium falciparum-infected Red Blood Cells
por: Hora, Rachna, et al.
Publicado: (2009)

A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells
por: Dai, Yuyuan, et al.
Publicado: (2021)

Casein Kinase 1α as a Regulator of Wnt-Driven Cancer
por: Shen, Chen, et al.
Publicado: (2020)

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo
por: Richter, Anna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2req2n7pmj2dhv65nv78blahj4