Overexpression of mouse TTF-2 gene causes cleft palate

In humans, mutations of the gene encoding for thyroid transcription factor-2 (TTF-2 or FOXE1) result in Bamforth syndrome. Bamforth syndrome is characterized by agenesis, cleft palate, spiky hair and choanal atresia. TTF-2 null mice (TTF-2(−/−)) also exhibit cleft palate, suggesting its involvement...

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Detalles Bibliográficos
Autores principales: Meng, Tian, Shi, Jia-Yu, Wu, Min, Wang, Yan, Li, Ling, Liu, Yan, Zheng, Qian, Huang, Lei, Shi, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823429/
https://www.ncbi.nlm.nih.gov/pubmed/22304410
http://dx.doi.org/10.1111/j.1582-4934.2012.01546.x

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