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Interaction between NO and COX pathways modulating hepatic endothelial cells from control and cirrhotic rats

Reduced intrahepatic nitric oxide (NO) bioavailability and increased cyclooxygenase-1 (COX-1)-derived vasoconstrictor prostanoids modulate the hepatic vascular tone in cirrhosis. We aimed at investigating the reciprocal interactions between NO and COX in the hepatic endothelium of control and cirrho...

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Detalles Bibliográficos
Autores principales: Rosado, Eugenio, Rodríguez-Vilarrupla, Aina, Gracia-Sancho, Jorge, Monclús, Montserrat, Bosch, Jaume, García-Pagán, Joan-Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823440/
https://www.ncbi.nlm.nih.gov/pubmed/22436078
http://dx.doi.org/10.1111/j.1582-4934.2012.01563.x

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