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Mankind’s first natural stem cell transplant

The timing of the umbilical cord clamping at birth is still controversial. In the modern era of medicine, the cord has been clamped early to facilitate resuscitation and stabilization of infants. However, recently delayed cord clamping has been supported by physicians because it allows for the physi...

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Detalles Bibliográficos
Autores principales: Tolosa, Jose N, Park, Dong-Hyuk, Eve, David J, Klasko, Stephen K, Borlongan, Cesario V, Sanberg, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823451/
https://www.ncbi.nlm.nih.gov/pubmed/20141549
http://dx.doi.org/10.1111/j.1582-4934.2010.01029.x
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author Tolosa, Jose N
Park, Dong-Hyuk
Eve, David J
Klasko, Stephen K
Borlongan, Cesario V
Sanberg, Paul R
author_facet Tolosa, Jose N
Park, Dong-Hyuk
Eve, David J
Klasko, Stephen K
Borlongan, Cesario V
Sanberg, Paul R
author_sort Tolosa, Jose N
collection PubMed
description The timing of the umbilical cord clamping at birth is still controversial. In the modern era of medicine, the cord has been clamped early to facilitate resuscitation and stabilization of infants. However, recently delayed cord clamping has been supported by physicians because it allows for the physiological transfer of blood from the placenta to the infant. Many clinical studies have revealed that the delayed cord clamping elevates blood volume and haemoglobin and prevents anaemia in infants. Moreover, since it was known that umbilical cord blood contains various valuable stem cells such as haematopoietic stem cells, endothelial cell precursors, mesenchymal progenitors and multipotent/pluripotent lineage stem cells, the merit of delayed cord clamping has been magnified. In this review, we discuss the advantages and disadvantages of delayed cord clamping at birth. We highlight the importance of delayed cord clamping in realizing mankind’s first stem cell transfer and propose that it should be encouraged in normal births.
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spelling pubmed-38234512015-04-20 Mankind’s first natural stem cell transplant Tolosa, Jose N Park, Dong-Hyuk Eve, David J Klasko, Stephen K Borlongan, Cesario V Sanberg, Paul R J Cell Mol Med Reviews The timing of the umbilical cord clamping at birth is still controversial. In the modern era of medicine, the cord has been clamped early to facilitate resuscitation and stabilization of infants. However, recently delayed cord clamping has been supported by physicians because it allows for the physiological transfer of blood from the placenta to the infant. Many clinical studies have revealed that the delayed cord clamping elevates blood volume and haemoglobin and prevents anaemia in infants. Moreover, since it was known that umbilical cord blood contains various valuable stem cells such as haematopoietic stem cells, endothelial cell precursors, mesenchymal progenitors and multipotent/pluripotent lineage stem cells, the merit of delayed cord clamping has been magnified. In this review, we discuss the advantages and disadvantages of delayed cord clamping at birth. We highlight the importance of delayed cord clamping in realizing mankind’s first stem cell transfer and propose that it should be encouraged in normal births. Blackwell Publishing Ltd 2010-03 2010-02-05 /pmc/articles/PMC3823451/ /pubmed/20141549 http://dx.doi.org/10.1111/j.1582-4934.2010.01029.x Text en © 2010 The Authors Journal compilation © 2010 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd
spellingShingle Reviews
Tolosa, Jose N
Park, Dong-Hyuk
Eve, David J
Klasko, Stephen K
Borlongan, Cesario V
Sanberg, Paul R
Mankind’s first natural stem cell transplant
title Mankind’s first natural stem cell transplant
title_full Mankind’s first natural stem cell transplant
title_fullStr Mankind’s first natural stem cell transplant
title_full_unstemmed Mankind’s first natural stem cell transplant
title_short Mankind’s first natural stem cell transplant
title_sort mankind’s first natural stem cell transplant
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823451/
https://www.ncbi.nlm.nih.gov/pubmed/20141549
http://dx.doi.org/10.1111/j.1582-4934.2010.01029.x
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