Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules

Understanding renal function requires one to integrate the structural complexity of kidney nephrons and the dynamic nature of their cellular processes. Multi-photon fluorescence microscopy is a state-of-the-art imaging technique for in vivo analysis of kidney tubules structure and function in real t...

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Autores principales: Caplanusi, A, Parreira, KS, Lima, W Rezende, Marien, B, Van Der Smissen, P, De Diesbach, P, Devuyst, O, Courtoy, PJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Images in Cellular / Molecular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823495/
https://www.ncbi.nlm.nih.gov/pubmed/18081693
http://dx.doi.org/10.1111/j.1582-4934.2007.00192.x
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author Caplanusi, A
Parreira, KS
Lima, W Rezende
Marien, B
Van Der Smissen, P
De Diesbach, P
Devuyst, O
Courtoy, PJ
author_facet Caplanusi, A
Parreira, KS
Lima, W Rezende
Marien, B
Van Der Smissen, P
De Diesbach, P
Devuyst, O
Courtoy, PJ
author_sort Caplanusi, A
collection PubMed
description Understanding renal function requires one to integrate the structural complexity of kidney nephrons and the dynamic nature of their cellular processes. Multi-photon fluorescence microscopy is a state-of-the-art imaging technique for in vivo analysis of kidney tubules structure and function in real time. This study presents visual evidence for several levels of heterogeneity of proximal tubular endocytic uptake in the superficial renal mouse cortex and illustrates the potential of multi-photon microscopy for providing a comprehensive and dynamic portrayal of renal function.
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spelling pubmed-38234952015-04-27 Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules Caplanusi, A Parreira, KS Lima, W Rezende Marien, B Van Der Smissen, P De Diesbach, P Devuyst, O Courtoy, PJ J Cell Mol Med Images in Cellular / Molecular Medicine Understanding renal function requires one to integrate the structural complexity of kidney nephrons and the dynamic nature of their cellular processes. Multi-photon fluorescence microscopy is a state-of-the-art imaging technique for in vivo analysis of kidney tubules structure and function in real time. This study presents visual evidence for several levels of heterogeneity of proximal tubular endocytic uptake in the superficial renal mouse cortex and illustrates the potential of multi-photon microscopy for providing a comprehensive and dynamic portrayal of renal function. Blackwell Publishing Ltd 2008-01 2007-12-10 /pmc/articles/PMC3823495/ /pubmed/18081693 http://dx.doi.org/10.1111/j.1582-4934.2007.00192.x Text en 2008 The Authors Journal compilation © 2008 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd
spellingShingle Images in Cellular / Molecular Medicine
Caplanusi, A
Parreira, KS
Lima, W Rezende
Marien, B
Van Der Smissen, P
De Diesbach, P
Devuyst, O
Courtoy, PJ
Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title_full Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title_fullStr Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title_full_unstemmed Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title_short Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
title_sort intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules
topic Images in Cellular / Molecular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823495/
https://www.ncbi.nlm.nih.gov/pubmed/18081693
http://dx.doi.org/10.1111/j.1582-4934.2007.00192.x
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