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Promiscuous RNA binding by Polycomb Repressive Complex 2

Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) recruit PRC2 to chromatin, but the general role of RNA in maintaining repressed chromatin is unknown. Here we measure the binding consta...

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Detalles Bibliográficos
Autores principales:	Davidovich, Chen, Zheng, Leon, Goodrich, Karen J., Cech, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823624/ https://www.ncbi.nlm.nih.gov/pubmed/24077223 http://dx.doi.org/10.1038/nsmb.2679

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