Cargando…
Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention
We previously demonstrated that mitochondrial bioenergetic deficits in the female brain accompanied reproductive senescence and was accompanied by a shift from an aerobic glycolytic to a ketogenic phenotype. Herein, we investigated the relationship between systems of fuel supply, transport and mitoc...
Autores principales: | Ding, Fan, Yao, Jia, Rettberg, Jamaica R., Chen, Shuhua, Brinton, Roberta Diaz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823655/ https://www.ncbi.nlm.nih.gov/pubmed/24244584 http://dx.doi.org/10.1371/journal.pone.0079977 |
Ejemplares similares
-
Ovariectomy Induces a Shift in Fuel Availability and Metabolism in the Hippocampus of the Female Transgenic Model of Familial Alzheimer's
por: Ding, Fan, et al.
Publicado: (2013) -
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease
por: Klosinski, Lauren P., et al.
Publicado: (2015) -
2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease
por: Yao, Jia, et al.
Publicado: (2011) -
Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery
por: Mosconi, Lisa, et al.
Publicado: (2017) -
Cognitive Declines Precede and Predict Functional Declines in Aging and Alzheimer’s Disease
por: Zahodne, Laura B., et al.
Publicado: (2013)