MiR-424/503-Mediated Rictor Upregulation Promotes Tumor Progression

mTOR complex 2 (mTORC2) signaling is upregulated in multiple types of human cancer, but the molecular mechanisms underlying its activation and regulation remain elusive. Here, we show that microRNA-mediated upregulation of Rictor, an mTORC2-specific component, contributes to tumor progression. Ricto...

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Detalles Bibliográficos
Autores principales: Oneyama, Chitose, Kito, Yoriko, Asai, Rei, Ikeda, Jun-ichiro, Yoshida, Takuya, Okuzaki, Daisuke, Kokuda, Rie, Kakumoto, Kyoko, Takayama, Ken-ichi, Inoue, Satoshi, Morii, Eiichi, Okada, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823661/
https://www.ncbi.nlm.nih.gov/pubmed/24244675
http://dx.doi.org/10.1371/journal.pone.0080300

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