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High-Mobility Group Box 1 Inhibits Gastric Ulcer Healing through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products
High-mobility group box 1 (HMGB1) was initially discovered as a nuclear protein that interacts with DNA as a chromatin-associated non-histone protein to stabilize nucleosomes and to regulate the transcription of many genes in the nucleus. Once leaked or actively secreted into the extracellular envir...
Autores principales: | Nadatani, Yuji, Watanabe, Toshio, Tanigawa, Tetsuya, Ohkawa, Fumikazu, Takeda, Shogo, Higashimori, Akira, Sogawa, Mitsue, Yamagami, Hirokazu, Shiba, Masatsugu, Watanabe, Kenji, Tominaga, Kazunari, Fujiwara, Yasuhiro, Takeuchi, Koji, Arakawa, Tetsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823709/ https://www.ncbi.nlm.nih.gov/pubmed/24244627 http://dx.doi.org/10.1371/journal.pone.0080130 |
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