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The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration

The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC stimulates the activity of the Cdc42- and Rac1-specific guanine nucleotide exchange factor Asef and promotes the migration and invasion of colorectal tumor cells. Furthermore, Asef is ove...

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Detalles Bibliográficos
Autores principales:	Furukawa, Shiori, Kawasaki, Yoshihiro, Miyamoto, Masaya, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823710/ https://www.ncbi.nlm.nih.gov/pubmed/24244701 http://dx.doi.org/10.1371/journal.pone.0080609

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