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Streptococcus pneumoniae Serine Protease HtrA, but Not SFP or PrtA, Is a Major Virulence Factor in Pneumonia
Streptococcus (S.) pneumoniae is a common causative pathogen in pneumonia. Serine protease orthologs expressed by a variety of bacteria have been found of importance for virulence. Previous studies have identified two serine proteases in S. pneumoniae, HtrA (high-temperature requirement A) and PrtA...
Autores principales: | de Stoppelaar, Sacha F., Bootsma, Hester J., Zomer, Aldert, Roelofs, Joris J. T. H., Hermans, Peter W. M., van ’t Veer, Cornelis, van der Poll, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823867/ https://www.ncbi.nlm.nih.gov/pubmed/24244609 http://dx.doi.org/10.1371/journal.pone.0080062 |
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