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On the Importance of Oxidative Folding in the Evolution of Conotoxins: Cysteine Codon Preservation through Gene Duplication and Adaptation
Conotoxin genes are among the most rapidly evolving genes currently known; however, despite the well-established hypervariability of the intercysteine loops, the cysteines demonstrate significant conservation, with a site-specific codon bias for each cysteine in a family of conotoxins. Herein we pre...
Autores principales: | Steiner, Andrew M., Bulaj, Grzegorz, Puillandre, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823881/ https://www.ncbi.nlm.nih.gov/pubmed/24244311 http://dx.doi.org/10.1371/journal.pone.0078456 |
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