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An Integrated Inspection of the Somatic Mutations in a Lung Squamous Cell Carcinoma Using Next-Generation Sequencing
Squamous cell carcinoma (SCC) of the lung kills over 350,000 people annually worldwide, and is the main lung cancer histotype with no targeted treatments. High-coverage whole-genome sequencing of the other main subtypes, small-cell and adenocarcinoma, gave insights into carcinogenic mechanisms and d...
Autores principales: | Stead, Lucy F., Egan, Philip, Devery, Aoife, Conway, Caroline, Daly, Catherine, Berri, Stefano, Wood, Henry, Belvedere, Ornella, Papagiannopoulos, Kostas, Ryan, Anderson, Rabbitts, Pamela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823931/ https://www.ncbi.nlm.nih.gov/pubmed/24244370 http://dx.doi.org/10.1371/journal.pone.0078823 |
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