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Requirement of SLD5 for Early Embryogenesis

SLD5 forms a GINS complex with PSF1, PSF2 and PSF3, which is essential for the initiation of DNA replication in lower eukaryotes. Although these components are conserved in mammals, their biological function is unclear. We show here that targeted disruption of SLD5 in mice causes a defect in cell pr...

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Detalles Bibliográficos
Autores principales: Mohri, Tomomi, Ueno, Masaya, Nagahama, Yumi, Gong, Zhi-Yuan, Asano, Masahide, Oshima, Hiroko, Oshima, Masanobu, Fujio, Yasushi, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823970/
https://www.ncbi.nlm.nih.gov/pubmed/24244394
http://dx.doi.org/10.1371/journal.pone.0078961