Cargando…

Efficacy of Cyclin Dependent Kinase 4 Inhibitors as Potent Neuroprotective Agents against Insults Relevant to Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with no cure till today. Aberrant activation of cell cycle regulatory proteins is implicated in neurodegenerative diseases including AD. We and others have shown that Cyclin dependent kinase 4 (Cdk4) is activated in AD brain and is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanphui, Priyankar, Pramanik, Sumit Kumar, Chatterjee, Nandini, Moorthi, Ponnusamy, Banerji, Biswadip, Biswas, Subhas Chandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823981/ https://www.ncbi.nlm.nih.gov/pubmed/24244372 http://dx.doi.org/10.1371/journal.pone.0078842

Ejemplares similares

Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development
por: Biswas, Subhas Chandra, et al.
Publicado: (2017)

Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid
por: Chatterjee, Nandini, et al.
Publicado: (2016)

Potent anticancer activity of cystine-based dipeptides and their interaction with serum albumins
por: Banerji, Biswadip, et al.
Publicado: (2013)

Binding studies of creatinine and urea on iron-nanoparticle
por: Banerji, Biswadip, et al.
Publicado: (2015)

Binding interaction of a novel fluorophore with serum albumins: steady state fluorescence perturbation and molecular modeling analysis
por: Pal, Uttam, et al.
Publicado: (2015)

Binding interaction of a gamma-aminobutyric acid derivative with serum albumin: an insight by fluorescence and molecular modeling analysis
por: Pal, Uttam, et al.
Publicado: (2016)

Silver-catalysed azide–alkyne cycloaddition (AgAAC): assessing the mechanism by density functional theory calculations
por: Banerji, Biswadip, et al.
Publicado: (2016)

Solvent-Assisted Tyrosine-Based Dipeptide Forms Low-Molecular Weight Gel: Preparation and Its Potential Use in Dye Removal and Oil Spillage Separation from Water
por: Majumder, Leena, et al.
Publicado: (2019)

Haloalkane induced hepatic insult in murine model: amelioration by Oleander through antioxidant and anti-inflammatory activities, an in vitro and in vivo study
por: Dey, Priyankar, et al.
Publicado: (2016)

Remote tissue conditioning is neuroprotective against MPTP insult in mice
por: Kim, Boaz, et al.
Publicado: (2018)

Primary pelvic hydatid cyst in a postmenopausal female: a surgical challenge
por: Paul, Sayanti, et al.
Publicado: (2017)

Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia
por: Wood, Thomas, et al.
Publicado: (2016)

Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult
por: Tang, Hao, et al.
Publicado: (2015)

Combination of Therapeutic Hypothermia and Other Neuroprotective Strategies after An Ischemic Cerebral Insult#
por: Goossens, Joline, et al.
Publicado: (2014)

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection
por: Peng, Xiao Chun, et al.
Publicado: (2018)

FoxO3a is activated and executes neuron death via Bim in response to β-amyloid
por: Sanphui, P, et al.
Publicado: (2013)

Cell-imaging studies of highly substituted oxazole derivatives as organelle targeting fluorophores (OTFPs)
por: Adhikary, Saswati, et al.
Publicado: (2022)

Ex Vivo and In Vivo Neuroprotection Induced by Argon When Given after an Excitotoxic or Ischemic Insult
por: David, Hélène N., et al.
Publicado: (2012)

Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult
por: Ferrer-Acosta, Yancy, et al.
Publicado: (2022)

Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention
por: Rynearson, Kevin D., et al.
Publicado: (2021)

Some Insults are Easier to Detect: The Embodied Insult Detection Effect
por: Wellsby, Michele, et al.
Publicado: (2010)

Chlorogenic Acid Improves Neuroprotective Effect of PEP-1-Ribosomal Protein S3 Against Ischemic Insult
por: Ahn, Eun Hee, et al.
Publicado: (2011)

Berberine chloride pretreatment exhibits neuroprotective effect against 6-hydroxydopamine-induced neuronal insult in rat
por: Negahdar, Feraidoon, et al.
Publicado: (2015)

Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases
por: Le Nogue, Déborah, et al.
Publicado: (2019)

Activation and Regulation of NLRP3 by Sterile and Infectious Insults
por: Banerjee, Srijon K., et al.
Publicado: (2022)

Activation of Endogenous Retrovirus, Brain Infections and Environmental Insults in Neurodegeneration and Alzheimer’s Disease
por: Licastro, Federico, et al.
Publicado: (2021)

The role of peripheral inflammatory insults in Alzheimer’s disease: a review and research roadmap
por: Walker, Keenan A., et al.
Publicado: (2023)

Erratum: Chlorogenic Acid Improves Neuroprotective Effect of PEP-1-Ribosomal Protein S3 Against Ischemic Insult
por: Ahn, Eun Hee, et al.
Publicado: (2012)

In vitro evidence for post-insult neuroprotective activity of an evolutionarily conserved motif against excitotoxic neuronal cell death
por: Tran, Phu V.
Publicado: (2019)

An Overview of Recent Advances in the Neuroprotective Potentials of Fisetin against Diverse Insults in Neurological Diseases and the Underlying Signaling Pathways
por: Tang, Xiangwen, et al.
Publicado: (2023)

Insult to newborn immunity.
por: Tibbetts, John
Publicado: (2003)

Adding Insult to Infection
por: Susman, E
Publicado: (2002)

Shakespeare's insults : educating your wit /
por: Shakespeare, William, 1564-1616
Publicado: (1995)

Persistent cerebral desaturation on near-infrared spectroscopy without neurological insult
por: Natarajan, Pooja, et al.
Publicado: (2018)

Molecular programs induced by heat acclimation confer neuroprotection against TBI and hypoxic insults via cross-tolerance mechanisms
por: Horowitz, Michal, et al.
Publicado: (2015)

Chemically Bonding of Amantadine with Gardenamide A Enhances the Neuroprotective Effects against Corticosterone-Induced Insults in PC12 Cells
por: Zhao, Jiaqiang, et al.
Publicado: (2015)

Rank hypocrisies: the insult of the REF
por: Sayer, Derek
Publicado: (2015)

Is Housing a Health Insult?
por: Baker, Emma, et al.
Publicado: (2017)

VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult
por: Ryu, Jae K, et al.
Publicado: (2008)

Inhibition of Neuronal p38α, but not p38β MAPK, Provides Neuroprotection Against Three Different Neurotoxic Insults
por: Xing, Bin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8bd6b6rtkreo1uigl8ioqamlr2