Cargando…

Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression()

BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...

Descripción completa

Detalles Bibliográficos
Autores principales: Groselj, Blaz, Kerr, Martin, Kiltie, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824066/
https://www.ncbi.nlm.nih.gov/pubmed/23932191
http://dx.doi.org/10.1016/j.radonc.2013.06.021