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Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation

The AGC family serine–threonine kinases Akt and Sgk are similar in primary amino acid sequence and in vitro substrate specificity, and both kinases are thought to directly phosphorylate and inhibit FoxO transcription factors. In the nematode Caenorhabditis elegans, it is well established that AKT-1...

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Detalles Bibliográficos
Autores principales:	Chen, Albert Tzong-Yang, Guo, Chunfang, Dumas, Kathleen J, Ashrafi, Kaveh, Hu, Patrick J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824081/ https://www.ncbi.nlm.nih.gov/pubmed/23786484 http://dx.doi.org/10.1111/acel.12120

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