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Gene-based multiple regression association testing for combined examination of common and low frequency variants in quantitative trait analysis
Multi-marker methods for genetic association analysis can be performed for common and low frequency SNPs to improve power. Regression models are an intuitive way to formulate multi-marker tests. In previous studies we evaluated regression-based multi-marker tests for common SNPs, and through identif...
Autores principales: | Yoo, Yun Joo, Sun, Lei, Bull, Shelley B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824159/ https://www.ncbi.nlm.nih.gov/pubmed/24273553 http://dx.doi.org/10.3389/fgene.2013.00233 |
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