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Selective anticancer agents suppress aging in Drosophila
Mutations of the PI3K, TOR, iNOS, and NF-κB genes increase lifespan of model organisms and reduce the risk of some aging-associated diseases. We studied the effects of inhibitors of PI3K (wortmannin), TOR (rapamycin), iNOS (1400W), NF-κB (pyrrolidin dithiocarbamate and QNZ), and the combined effects...
Autores principales: | Danilov, Anton, Shaposhnikov, Mikhail, Plyusnina, Ekaterina, Kogan, Valeria, Fedichev, Peter, Moskalev, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824538/ https://www.ncbi.nlm.nih.gov/pubmed/24096697 |
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