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Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes
Oxidative stress contributes to dysfunction of glial cells in the optic nerve head (ONH). However, the biological basis of the precise functional role of mitochondria in this dysfunction is not fully understood. Coenzyme Q10 (CoQ(10)), an essential cofactor of the electron transport chain and a pote...
Autores principales: | Noh, Y H, Kim, K-Y, Shim, M S, Choi, S-H, Choi, S, Ellisman, M H, Weinreb, R N, Perkins, G A, Ju, W-K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824651/ https://www.ncbi.nlm.nih.gov/pubmed/24091663 http://dx.doi.org/10.1038/cddis.2013.341 |
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