Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision

Gpr97 is an orphan adhesion GPCR and is highly conserved among species. Up to now, its physiological function remains largely unknown. Here, we show that Gpr97 deficiency results in an extensive reduction in B220(+) lymphocytes in mice. More intensive analyses reveal an expanded marginal zone but a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, J-j, Zhang, L-l, Zhang, Hong-x, Shen, C-l, Lu, S-y, Kuang, Y, Wan, Y-h, Wang, W-g, Yan, H-m, Dang, S-y, Fei, J, Jin, X-l, Wang, Z-g
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824656/
https://www.ncbi.nlm.nih.gov/pubmed/24113187
http://dx.doi.org/10.1038/cddis.2013.346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824656/
https://www.ncbi.nlm.nih.gov/pubmed/24113187
http://dx.doi.org/10.1038/cddis.2013.346

Ejemplares similares