Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation

Dexamethasone (Dex)-induced osteoporosis has been described as the most severe side effect in long-term glucocorticoid therapy. The decreased bone mass and the increased marrow fat suggest that Dex possibly shifts the differentiation of bone marrow stromal cells (BMSCs) to favor adipocyte over osteo...

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Detalles Bibliográficos
Autores principales: Li, J, Zhang, N, Huang, X, Xu, J, Fernandes, J C, Dai, K, Zhang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824658/
https://www.ncbi.nlm.nih.gov/pubmed/24091675
http://dx.doi.org/10.1038/cddis.2013.348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824658/
https://www.ncbi.nlm.nih.gov/pubmed/24091675
http://dx.doi.org/10.1038/cddis.2013.348

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