Opposing effects of high- and low-molecular weight hyaluronan on CXCL12-induced CXCR4 signaling depend on CD44

The tumor microenvironment makes a decisive contribution to the development and dissemination of cancer, for example, through extracellular matrix components such as hyaluronan (HA), and through chemokines that regulate tumor cell behavior and angiogenesis. Here we report a molecular link between HA...

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Detalles Bibliográficos
Autores principales: Fuchs, K, Hippe, A, Schmaus, A, Homey, B, Sleeman, J P, Orian-Rousseau, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824673/
https://www.ncbi.nlm.nih.gov/pubmed/24091662
http://dx.doi.org/10.1038/cddis.2013.364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824673/
https://www.ncbi.nlm.nih.gov/pubmed/24091662
http://dx.doi.org/10.1038/cddis.2013.364

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