A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency

Primary ovarian insufficiency (POI), or premature ovarian failure, is defined as the cessation of ovarian function before the age of 40. An insufficient ovarian follicle pool derived from primordial germ cells (PGCs) is an important cause of POI. Although the Nanos gene family is known to be require...

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Detalles Bibliográficos
Autores principales: Wu, X, Wang, B, Dong, Z, Zhou, S, Liu, Z, Shi, G, Cao, Y, Xu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824677/
https://www.ncbi.nlm.nih.gov/pubmed/24091668
http://dx.doi.org/10.1038/cddis.2013.368

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