Cargando…

Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe

Chromosomal missegregation is a common feature of many human tumors. Recent studies have indicated a link between nucleoporin RanBP2/Nup358 and chromosomal segregation during mitosis; however, the molecular details have yet to be fully established. Observed through live cell imaging and flow cytomet...

Descripción completa

Detalles Bibliográficos
Autores principales: Hashizume, C, Kobayashi, A, Wong, R W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824679/
https://www.ncbi.nlm.nih.gov/pubmed/24113188
http://dx.doi.org/10.1038/cddis.2013.370