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HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1

HIV-1 glycoprotein 120 (gp120) is known to cause neurotoxicity via several mechanisms including production of proinflammatory cytokines/chemokines and oxidative stress. Likewise, drug abuse is thought to have a direct impact on the pathology of HIV-associated neuroinflammation through the induction...

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Detalles Bibliográficos
Autores principales: Shah, A, Kumar, S, Simon, S D, Singh, D P, Kumar, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824683/
https://www.ncbi.nlm.nih.gov/pubmed/24113184
http://dx.doi.org/10.1038/cddis.2013.374