The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells

The inherent resistance of tumors to DNA damage often limits the efficacy of chemotherapy. The aim of this work is to explore the potential mechanism for development of chemoresistance in gastric cancer. Our data revealed that AKT1 mRNA and protein expression were induced by doxorubicin (a chemother...

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Detalles Bibliográficos
Autores principales: Zhou, W, Fu, X-Q, Zhang, L-L, Zhang, J, Huang, X, Lu, X-H, Shen, L, Liu, B-N, Liu, J, Luo, H-S, Yu, J-P, Yu, H-G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824684/
https://www.ncbi.nlm.nih.gov/pubmed/24113181
http://dx.doi.org/10.1038/cddis.2013.375

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