IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway

Interferon regulatory factor-4 binding protein (IBP) is a novel upstream activator of Rho GTPases. Our previous studies have shown that ectopic expression of IBP was correlated with malignant behaviors of human breast cancer cells, and invasive human breast cancer had high expression of IBP that pro...

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Detalles Bibliográficos
Autores principales: Chen, S, Han, Q, Wang, X, Yang, M, Zhang, Z, Li, P, Chen, A, Hu, C, Li, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824689/
https://www.ncbi.nlm.nih.gov/pubmed/24113176
http://dx.doi.org/10.1038/cddis.2013.380

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