Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain

BACKGROUND: We performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool (BLAST) of a complete Human Rotavirus (HRV) genome isolated from a hospitalized child with acute gastroenteritis in Thailand. FINDINGS: The results indicated an uncommon strain characterized by multiple...

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Autores principales: Theamboonlers, Apiradee, Maiklang, Ornwalan, Thongmee, Thanunrat, Chieochansin, Thaweesak, Vuthitanachot, Viboonsuk, Poovorawan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824699/
https://www.ncbi.nlm.nih.gov/pubmed/24255863
http://dx.doi.org/10.1186/2193-1801-2-569
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author Theamboonlers, Apiradee
Maiklang, Ornwalan
Thongmee, Thanunrat
Chieochansin, Thaweesak
Vuthitanachot, Viboonsuk
Poovorawan, Yong
author_facet Theamboonlers, Apiradee
Maiklang, Ornwalan
Thongmee, Thanunrat
Chieochansin, Thaweesak
Vuthitanachot, Viboonsuk
Poovorawan, Yong
author_sort Theamboonlers, Apiradee
collection PubMed
description BACKGROUND: We performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool (BLAST) of a complete Human Rotavirus (HRV) genome isolated from a hospitalized child with acute gastroenteritis in Thailand. FINDINGS: The results indicated an uncommon strain characterized by multiple re-assortments in the VP3, VP4, VP6, NSP1, NSP4 and NSP5 genes. The uncommon strain is genotype G3-P[9]-I3-R3-C3-M3-A3-N3-T3-E3-H6, which displays aspects of the AU-1, FRV-1 and corresponds to the feline/canine prototype G3P[9] strain. CONCLUSIONS: The results suggested that nearly all the eleven gene segments of G3P[9] RVA strain CU365 might have originated from feline/canine RVAs (Rotavirus A).
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spelling pubmed-38246992013-11-19 Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain Theamboonlers, Apiradee Maiklang, Ornwalan Thongmee, Thanunrat Chieochansin, Thaweesak Vuthitanachot, Viboonsuk Poovorawan, Yong Springerplus Short Report BACKGROUND: We performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool (BLAST) of a complete Human Rotavirus (HRV) genome isolated from a hospitalized child with acute gastroenteritis in Thailand. FINDINGS: The results indicated an uncommon strain characterized by multiple re-assortments in the VP3, VP4, VP6, NSP1, NSP4 and NSP5 genes. The uncommon strain is genotype G3-P[9]-I3-R3-C3-M3-A3-N3-T3-E3-H6, which displays aspects of the AU-1, FRV-1 and corresponds to the feline/canine prototype G3P[9] strain. CONCLUSIONS: The results suggested that nearly all the eleven gene segments of G3P[9] RVA strain CU365 might have originated from feline/canine RVAs (Rotavirus A). Springer International Publishing 2013-10-26 /pmc/articles/PMC3824699/ /pubmed/24255863 http://dx.doi.org/10.1186/2193-1801-2-569 Text en © Theamboonlers et al.; licensee Springer. 2013 This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Theamboonlers, Apiradee
Maiklang, Ornwalan
Thongmee, Thanunrat
Chieochansin, Thaweesak
Vuthitanachot, Viboonsuk
Poovorawan, Yong
Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title_full Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title_fullStr Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title_full_unstemmed Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title_short Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
title_sort complete genome analysis of a rare human g3p[9] rotavirus posing as an au-1 like strain
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824699/
https://www.ncbi.nlm.nih.gov/pubmed/24255863
http://dx.doi.org/10.1186/2193-1801-2-569
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