A Simple Oligonucleotide Biochip Capable of Rapidly Detecting Known Mitochondrial DNA Mutations in Chinese Patients with Leber’S Hereditary Optic Neuropathy (LHON)

Leber's hereditary optic neuropathy (LHON) is a maternally transmitted disease. Clinically, no efficient assay protocols have been available. In this study, we aimed to develop an oligonucleotide biochip specialized for detection of known base substitution mutations in mitochondrial DNA causing...

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Detalles Bibliográficos
Autores principales: Du, Wei-Dong, Chen, Gang, Cao, Hui-Min, Jin, Qing-Hui, Liao, Rong-Feng, He, Xiang-Cheng, Chen, Da-Ben, Huang, Shu-Ren, Zhao, Hui, Lv, Yong-Mei, Tang, Hua-Yang, Tang, Xian-Fa, Wang, Yong-Qing, Sun, Song, Zhao, Jian-Long, Zhang, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825074/
https://www.ncbi.nlm.nih.gov/pubmed/21694444
http://dx.doi.org/10.3233/DMA-2011-0767

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