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Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer

Arsenic, though a poor mutagen, is an accepted environmental carcinogen. Perturbation of DNA methylation pattern leading to aberrant gene expression has been hypothesized as the mechanism for arsenic induced carcinogenesis. We had earlier demonstrated the hypermethylation of promoter region of p53 a...

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Detalles Bibliográficos
Autores principales: Chanda, Sarmishtha, Dasgupta, Uma B, Mazumder, Debendranath Guha, Saha, Jayita, Gupta, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825097/
https://www.ncbi.nlm.nih.gov/pubmed/24255851
http://dx.doi.org/10.1186/2193-1801-2-557

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