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Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer
Arsenic, though a poor mutagen, is an accepted environmental carcinogen. Perturbation of DNA methylation pattern leading to aberrant gene expression has been hypothesized as the mechanism for arsenic induced carcinogenesis. We had earlier demonstrated the hypermethylation of promoter region of p53 a...
Autores principales: | Chanda, Sarmishtha, Dasgupta, Uma B, Mazumder, Debendranath Guha, Saha, Jayita, Gupta, Bhaskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825097/ https://www.ncbi.nlm.nih.gov/pubmed/24255851 http://dx.doi.org/10.1186/2193-1801-2-557 |
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