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Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population
AIMS/HYPOTHESIS: Candidate gene and genome-wide association studies have identified ∼60 susceptibility loci for type 2 diabetes. A majority of these loci have been discovered and tested only in European populations. The aim of this study was to assess the presence and extent of trans-ethnic effects...
Autores principales: | Kuo, Jane Z., Sheu, Wayne Huey-Herng, Assimes, Themistocles L., Hung, Yi-Jen, Absher, Devin, Chiu, Yen-Feng, Mak, Jordan, Wang, Jun-Sing, Kwon, Soonil, Hsu, Chih-Cheng, Goodarzi, Mark O., Lee, I-Te, Knowles, Joshua W., Miller, Brittany E., Lee, Wen-Jane, Juang, Jyh-Ming J., Wang, Tzung-Dau, Guo, Xiuqing, Taylor, Kent D., Chuang, Lee-Ming, Hsiung, Chao A., Quertermous, Thomas, Rotter, Jerome I., Chen, Yii-Der I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825282/ https://www.ncbi.nlm.nih.gov/pubmed/24013783 http://dx.doi.org/10.1007/s00125-013-3047-1 |
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