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Silibinin inhibits the production of pro-inflammatory cytokines through inhibition of NF-κB signaling pathway in HMC-1 human mast cells
BACKGROUND: Silibinin is the major active molecule of silymarin, the mixture of flavonolignans extracted from Cirsium japonicum. It has been used for the treatment of hepatitis and inflammation-related diseases. In the present study, the effects of silibinin on allergic inflammation and its signalin...
Autores principales: | Kim, Beom-Rak, Seo, Hye-Sook, Ku, Jin-Mo, Kim, Gyung-Jun, Jeon, Chan Yong, Park, Jong Hyeong, Jang, Bo-Hyoung, Park, Sun-Ju, Shin, Yong-Cheol, Ko, Seong-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825293/ https://www.ncbi.nlm.nih.gov/pubmed/24045679 http://dx.doi.org/10.1007/s00011-013-0640-1 |
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