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Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals
ABSTRACT: Terbium fluoride nanocrystals, covered by a shell, composed of cerium fluoride were synthesized by a co-precipitation method. Their complex structure was formed spontaneously during the synthesis. The surface of these core/shell nanocrystals was additionally modified by silica. The propert...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825480/ https://www.ncbi.nlm.nih.gov/pubmed/24273438 http://dx.doi.org/10.1007/s11051-013-1958-x |
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author | Grzyb, Tomasz Runowski, Marcin Dąbrowska, Krystyna Giersig, Michael Lis, Stefan |
author_facet | Grzyb, Tomasz Runowski, Marcin Dąbrowska, Krystyna Giersig, Michael Lis, Stefan |
author_sort | Grzyb, Tomasz |
collection | PubMed |
description | ABSTRACT: Terbium fluoride nanocrystals, covered by a shell, composed of cerium fluoride were synthesized by a co-precipitation method. Their complex structure was formed spontaneously during the synthesis. The surface of these core/shell nanocrystals was additionally modified by silica. The properties of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals, formed in this way, were investigated. Spectroscopic studies showed that the differences between these two groups of products resulted from the presence of the SiO(2) shell. X-ray diffraction patterns confirmed the trigonal crystal structure of TbF(3)@CeF(3) nanocrystals. High resolution transmission electron microscopy in connection with energy-dispersive X-ray spectroscopy showed a complex structure of the formed nanocrystals. Crystallized as small discs, ‘the products’, with an average diameter around 10 nm, showed an increase in the concentration of Tb(3+) ions from surface to the core of nanocrystals. In addition to photo-physical analyses, cytotoxicity studies were performed on HSkMEC (Human Skin Microvascular Endothelial Cells) and B16F0 mouse melanoma cancer cells. The cytotoxicity of the nanomaterials was neutral for the investigated cells with no toxic or antiproliferative effect in the cell cultures, either for normal or for cancer cells. This fact makes the obtained nanocrystals good candidates for biological applications and further modifications of the SiO(2) shell. GRAPHICAL ABSTRACT: . [Image: see text] |
format | Online Article Text |
id | pubmed-3825480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-38254802013-11-21 Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals Grzyb, Tomasz Runowski, Marcin Dąbrowska, Krystyna Giersig, Michael Lis, Stefan J Nanopart Res Research Paper ABSTRACT: Terbium fluoride nanocrystals, covered by a shell, composed of cerium fluoride were synthesized by a co-precipitation method. Their complex structure was formed spontaneously during the synthesis. The surface of these core/shell nanocrystals was additionally modified by silica. The properties of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals, formed in this way, were investigated. Spectroscopic studies showed that the differences between these two groups of products resulted from the presence of the SiO(2) shell. X-ray diffraction patterns confirmed the trigonal crystal structure of TbF(3)@CeF(3) nanocrystals. High resolution transmission electron microscopy in connection with energy-dispersive X-ray spectroscopy showed a complex structure of the formed nanocrystals. Crystallized as small discs, ‘the products’, with an average diameter around 10 nm, showed an increase in the concentration of Tb(3+) ions from surface to the core of nanocrystals. In addition to photo-physical analyses, cytotoxicity studies were performed on HSkMEC (Human Skin Microvascular Endothelial Cells) and B16F0 mouse melanoma cancer cells. The cytotoxicity of the nanomaterials was neutral for the investigated cells with no toxic or antiproliferative effect in the cell cultures, either for normal or for cancer cells. This fact makes the obtained nanocrystals good candidates for biological applications and further modifications of the SiO(2) shell. GRAPHICAL ABSTRACT: . [Image: see text] Springer Netherlands 2013-09-05 2013 /pmc/articles/PMC3825480/ /pubmed/24273438 http://dx.doi.org/10.1007/s11051-013-1958-x Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Research Paper Grzyb, Tomasz Runowski, Marcin Dąbrowska, Krystyna Giersig, Michael Lis, Stefan Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title | Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title_full | Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title_fullStr | Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title_full_unstemmed | Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title_short | Structural, spectroscopic and cytotoxicity studies of TbF(3)@CeF(3) and TbF(3)@CeF(3)@SiO(2) nanocrystals |
title_sort | structural, spectroscopic and cytotoxicity studies of tbf(3)@cef(3) and tbf(3)@cef(3)@sio(2) nanocrystals |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825480/ https://www.ncbi.nlm.nih.gov/pubmed/24273438 http://dx.doi.org/10.1007/s11051-013-1958-x |
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