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Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

PURPOSE: In the present study, we screened a compound library containing 1,600 clinically used compounds with the aim to identify compounds, which potentially could be repositioned for colon cancer therapy. METHODS: Two established colon cancer cell lines were tested using the fluorometric microcult...

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Detalles Bibliográficos
Autores principales: Nygren, Peter, Fryknäs, Mårten, Ågerup, Bengt, Larsson, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825534/
https://www.ncbi.nlm.nih.gov/pubmed/24135855
http://dx.doi.org/10.1007/s00432-013-1539-5