Tumor-targeting vaccination instructs graft-vs.-tumor immune responses

Anticancer vaccines hold the potential to promote tumor eradication by immune effector cells. We have recently found dendritic cell-based vaccines to instruct graft-vs.-tumor responses following allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusion. Vaccination was essenti...

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Autores principales: Manzo, Teresa, Michelini, Rodrigo Hess, Sturmheit, Tabea, Basso, Veronica, Bellone, Matteo, Mondino, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825719/
https://www.ncbi.nlm.nih.gov/pubmed/24244899
http://dx.doi.org/10.4161/onci.25996
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author Manzo, Teresa
Michelini, Rodrigo Hess
Sturmheit, Tabea
Basso, Veronica
Bellone, Matteo
Mondino, Anna
author_facet Manzo, Teresa
Michelini, Rodrigo Hess
Sturmheit, Tabea
Basso, Veronica
Bellone, Matteo
Mondino, Anna
author_sort Manzo, Teresa
collection PubMed
description Anticancer vaccines hold the potential to promote tumor eradication by immune effector cells. We have recently found dendritic cell-based vaccines to instruct graft-vs.-tumor responses following allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusion. Vaccination was essential to elicit the intratumoral expression of interferon γ, promote local inflammation, and stimulate therapeutic T-cell infiltration.
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spelling pubmed-38257192013-11-15 Tumor-targeting vaccination instructs graft-vs.-tumor immune responses Manzo, Teresa Michelini, Rodrigo Hess Sturmheit, Tabea Basso, Veronica Bellone, Matteo Mondino, Anna Oncoimmunology Author's View Anticancer vaccines hold the potential to promote tumor eradication by immune effector cells. We have recently found dendritic cell-based vaccines to instruct graft-vs.-tumor responses following allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusion. Vaccination was essential to elicit the intratumoral expression of interferon γ, promote local inflammation, and stimulate therapeutic T-cell infiltration. Landes Bioscience 2013-10-01 2013-09-12 /pmc/articles/PMC3825719/ /pubmed/24244899 http://dx.doi.org/10.4161/onci.25996 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Manzo, Teresa
Michelini, Rodrigo Hess
Sturmheit, Tabea
Basso, Veronica
Bellone, Matteo
Mondino, Anna
Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title_full Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title_fullStr Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title_full_unstemmed Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title_short Tumor-targeting vaccination instructs graft-vs.-tumor immune responses
title_sort tumor-targeting vaccination instructs graft-vs.-tumor immune responses
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825719/
https://www.ncbi.nlm.nih.gov/pubmed/24244899
http://dx.doi.org/10.4161/onci.25996
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