Extending the chimeric receptor-based T-cell targeting strategy to solid tumors

The adoptive transfer of T cells expressing chimeric antigen receptors (CARs) has emerged as a promising immunotherapeutic strategy against cancer. Administering CAR-expressing T cells in combination with agents that promote the expression of CAR targets or optimize T-cell function within the tumor...

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Detalles Bibliográficos
Autor principal: Rossig, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825720/
https://www.ncbi.nlm.nih.gov/pubmed/24244901
http://dx.doi.org/10.4161/onci.26091
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author Rossig, Claudia
author_facet Rossig, Claudia
author_sort Rossig, Claudia
collection PubMed
description The adoptive transfer of T cells expressing chimeric antigen receptors (CARs) has emerged as a promising immunotherapeutic strategy against cancer. Administering CAR-expressing T cells in combination with agents that promote the expression of CAR targets or optimize T-cell function within the tumor microenvironment may further improve the therapeutic potential of this approach.
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spelling pubmed-38257202013-11-15 Extending the chimeric receptor-based T-cell targeting strategy to solid tumors Rossig, Claudia Oncoimmunology Author's View The adoptive transfer of T cells expressing chimeric antigen receptors (CARs) has emerged as a promising immunotherapeutic strategy against cancer. Administering CAR-expressing T cells in combination with agents that promote the expression of CAR targets or optimize T-cell function within the tumor microenvironment may further improve the therapeutic potential of this approach. Landes Bioscience 2013-10-01 2013-09-12 /pmc/articles/PMC3825720/ /pubmed/24244901 http://dx.doi.org/10.4161/onci.26091 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Rossig, Claudia
Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title_full Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title_fullStr Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title_full_unstemmed Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title_short Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
title_sort extending the chimeric receptor-based t-cell targeting strategy to solid tumors
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825720/
https://www.ncbi.nlm.nih.gov/pubmed/24244901
http://dx.doi.org/10.4161/onci.26091
work_keys_str_mv AT rossigclaudia extendingthechimericreceptorbasedtcelltargetingstrategytosolidtumors

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