BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation

Although in the last few years γδ T lymphocytes have been the subject of growing interest as potential anticancer immunotherapeutics, how the proliferative and effector responses of these cells are regulated remains unclear. We have recently reported that the co-receptor B and T lymphocyte associate...

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Autores principales: Gertner-Dardenne, Julie, Fauriat, Cyril, Olive, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825728/
https://www.ncbi.nlm.nih.gov/pubmed/24244908
http://dx.doi.org/10.4161/onci.25853
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author Gertner-Dardenne, Julie
Fauriat, Cyril
Olive, Daniel
author_facet Gertner-Dardenne, Julie
Fauriat, Cyril
Olive, Daniel
author_sort Gertner-Dardenne, Julie
collection PubMed
description Although in the last few years γδ T lymphocytes have been the subject of growing interest as potential anticancer immunotherapeutics, how the proliferative and effector responses of these cells are regulated remains unclear. We have recently reported that the co-receptor B and T lymphocyte associated (BTLA) inhibits the proliferation of human Vγ9Vδ2 T cells, potentially underpinning a mechanism of immune escape by lymphoma cells.
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spelling pubmed-38257282013-11-15 BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation Gertner-Dardenne, Julie Fauriat, Cyril Olive, Daniel Oncoimmunology Author's View Although in the last few years γδ T lymphocytes have been the subject of growing interest as potential anticancer immunotherapeutics, how the proliferative and effector responses of these cells are regulated remains unclear. We have recently reported that the co-receptor B and T lymphocyte associated (BTLA) inhibits the proliferation of human Vγ9Vδ2 T cells, potentially underpinning a mechanism of immune escape by lymphoma cells. Landes Bioscience 2013-09-01 2013-07-29 /pmc/articles/PMC3825728/ /pubmed/24244908 http://dx.doi.org/10.4161/onci.25853 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Gertner-Dardenne, Julie
Fauriat, Cyril
Olive, Daniel
BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title_full BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title_fullStr BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title_full_unstemmed BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title_short BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
title_sort btla, a key regulator of vγ9vδ2 t-cell proliferation
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825728/
https://www.ncbi.nlm.nih.gov/pubmed/24244908
http://dx.doi.org/10.4161/onci.25853
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