Tumor-infiltrating follicular helper T cells: The new kids on the block

By analyzing CD4(+) lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized CD4(+) T cells, which localize to the germinal centers of peritumoral tertiary lymp...

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Detalles Bibliográficos
Autores principales: Gu-Trantien, Chunyan, Willard-Gallo, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825729/
https://www.ncbi.nlm.nih.gov/pubmed/24244900
http://dx.doi.org/10.4161/onci.26066
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author Gu-Trantien, Chunyan
Willard-Gallo, Karen
author_facet Gu-Trantien, Chunyan
Willard-Gallo, Karen
author_sort Gu-Trantien, Chunyan
collection PubMed
description By analyzing CD4(+) lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized CD4(+) T cells, which localize to the germinal centers of peritumoral tertiary lymphoid structures found in extensively infiltrated neoplastic lesions, predicts improved disease outcome among breast carcinoma patients.
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spelling pubmed-38257292013-11-15 Tumor-infiltrating follicular helper T cells: The new kids on the block Gu-Trantien, Chunyan Willard-Gallo, Karen Oncoimmunology Author's View By analyzing CD4(+) lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized CD4(+) T cells, which localize to the germinal centers of peritumoral tertiary lymphoid structures found in extensively infiltrated neoplastic lesions, predicts improved disease outcome among breast carcinoma patients. Landes Bioscience 2013-10-01 2013-09-12 /pmc/articles/PMC3825729/ /pubmed/24244900 http://dx.doi.org/10.4161/onci.26066 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Gu-Trantien, Chunyan
Willard-Gallo, Karen
Tumor-infiltrating follicular helper T cells: The new kids on the block
title Tumor-infiltrating follicular helper T cells: The new kids on the block
title_full Tumor-infiltrating follicular helper T cells: The new kids on the block
title_fullStr Tumor-infiltrating follicular helper T cells: The new kids on the block
title_full_unstemmed Tumor-infiltrating follicular helper T cells: The new kids on the block
title_short Tumor-infiltrating follicular helper T cells: The new kids on the block
title_sort tumor-infiltrating follicular helper t cells: the new kids on the block
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825729/
https://www.ncbi.nlm.nih.gov/pubmed/24244900
http://dx.doi.org/10.4161/onci.26066
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AT willardgallokaren tumorinfiltratingfollicularhelpertcellsthenewkidsontheblock

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